Comprehensive analysis of the 16p11.2 deletion and null cntnap2 mouse models of autism spectrum disorder.

For: All,

This study shows that mice with a 16p11.2 deletion were smaller and more physically active than typical mice but did not have clear social difficulties, suggesting that this genetic condition may affect movement and development more than social behavior and highlighting the importance of personalized approaches to support and treatment for families affected by 16p11.2 syndromes.