TAOK2 drives opposing cilia length deficits in 16p11.2 deletion and duplication carriers.

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This early research study suggests that both 16p11.2 deletions and duplications affect how brain cells grow and communicate by changing tiny cell structures called cilia—growing too long in deletions and too short in duplications— helping families understand that differences seen in development and behavior have real biological roots and may guide future research toward targeted treatments (though this is not yet clinical care).