Age-aware genotype–phenotype architecture across 87 genetic neurodevelopmental disorders.

For: All,

This large study shows that genetic conditions like 16p11.2 deletions and duplications affect many body systems and change how risks unfold as children grow, helping families and care teams use age‑specific, gene‑informed information to anticipate when challenges (such as seizures or learning differences) are most likely to appear and plan monitoring and supports more proactively.