Autism spectrum disorder susceptibility gene TAOK2 affects basal dendrite formation in the neocortex.

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This study examines the TAOK2 gene, located in the 16p11.2 proximal region, and finds that it plays a critical role in how brain cells grow their branch-like connections (dendrites), which may help explain some of the neurological differences seen in children with 16p11.2 proximal deletions or duplications.