Day-to-day spontaneous social behaviours is quantitatively and qualitatively affected in a 16p11.2 deletion mouse model.

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Researchers studying mice with the 16p11.2 proximal deletion found that these mice showed notable social behavior differences and increased movement compared to typical mice, with males showing more social deficits than females, suggesting that longer observation periods give a more complete picture of how this deletion affects behavior—which may help guide future therapies for families.