Deletion and duplication of 16p11.2 are associated with opposing effects on visual evoked potential amplitude.

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This study shows that children with a 16p11.2 deletion process visual information more strongly than typical children, while those with a duplication process it less strongly, suggesting that a simple, noninvasive brain test (EEG with visual patterns) could help doctors better understand how 16p11.2 differences affect brain development and sensory experiences in individual children.