Differential Short-Term Plasticity of PV and SST Neurons Accounts for Adaptation and Facilitation of Cortical Neurons to Auditory Tones.

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This neuroscience study helps explain why some children—including many with 16p11.2—may be overly sensitive to repeated sounds or struggle to “tune out” noise, showing that differences in specific brain cells can change how the brain adapts to sounds over time and affect everyday listening, language, and sensory comfort.