Drug-responsive autism phenotypes in the 16p11.2 deletion mouse model: a central role for gene-environment interactions.

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This study in a proximal 16p11.2 deletion mouse model suggests that autism‑related behaviors may become more noticeable during stress and can improve with certain medications (like N‑acetylcysteine), helping families understand that environment and stress matter—and that future treatments might one day be tailored to support emotional regulation and reduce challenges during stressful situations, though this work is still experimental and not yet a treatment recommendation.