Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.

For: All,

This study identified genetic variants linked to pubertal growth, timing of puberty, and childhood obesity, including a variant near the MAPK3 gene—which lies within the 16p11.2 proximal region—suggesting that changes in this gene may influence when and how children grow during puberty, which may be relevant to families affected by 16p11.2 proximal deletions or duplications.