Identification of rare variants in KCTD13 at the schizophrenia risk locus 16p11.2.

For: All,

This study explored the role of a specific gene called KCTD13, located within the 16p11.2 region, in schizophrenia risk by sequencing it in nearly 600 patients and identifying two rare mutations that may affect brain development, suggesting that families with 16p11.2 duplications should be aware of this gene's potential contribution to psychiatric outcomes.