Rock2 heterozygosity improves recognition memory and endothelial function in a mouse model of 16p11.2 deletion autism syndrome.

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This mouse study suggests that gently reducing the activity of a gene called ROCK2 can improve memory and brain blood‑vessel health in 16p11.2 deletion models, offering early but hopeful clues that targeting this pathway might one day help support learning and brain function in people with 16p11.2 syndromes.