Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance.
All,
This research article explains how the Raf/MEK/ERK signaling pathway — which helps control cell growth and survival — can become overactive in certain cancers, and while not specific to 16p11.2, families may find it relevant background for understanding how shared cellular signaling pathways (sometimes implicated in neurodevelopmental conditions) can influence cell behavior and treatment strategies.