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Structural models of genome-wide covariance identify multiple common dimensions in autism.

All Variants,

All,

This study shows that autism is shaped by several shared genetic pathways—especially those affecting language, behavior, and motor development—which helps explain why children with genetic conditions like 16p11.2 syndromes can have very different strengths and challenges, reinforcing that each child’s profile is unique and needs individualized understanding and support.

ASD,