Home > Resources > Targeting the RHOA pathway improves learning and memory in adult Kctd13 and 16p11.2 deletion mouse models.

Targeting the RHOA pathway improves learning and memory in adult Kctd13 and 16p11.2 deletion mouse models.

Proximal Deletion,

All,

Researchers found that a drug called fasudil, which targets a specific brain signaling pathway (RHOA), helped improve learning and memory in mice with the 16p11.2 deletion, pointing to a potential treatment strategy for cognitive challenges in people with this deletion.

Pathophysiology,