The pleiotropic spectrum of proximal 16p11.2 CNVs.

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This up‑to‑date review explains that proximal 16p11.2 deletions and duplications can affect many body and brain systems in very different ways from person to person, helping families understand why symptoms vary so widely and how this knowledge can be used to support personalized medical monitoring, anticipatory guidance, and tailored interventions instead of expecting a single, predictable profile.